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X-FROM-URL:https://eom.sdu.dk/events/ical/74f5e3fc-bb03-4939-ae66-c8af27fb
 6db6
X-WR-CALNAME:DIAS Nobel Colloquium: Morten Meldal\, Danish Nobel Prize-Win
 ner
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TZID:Europe/Copenhagen
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DTSTART:20261028T030000
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DESCRIPTION:[b]Molecular Click Adventures. A Leap from the Shoulders of Gi
 ants.[/b] [nl][nl]\nAbstract: [nl]\nThe concept of click chemistry mature
 d simultaneously in different laboratories around the world in the 1990’s
 . There was an urgent need for quantitative chemical reactions/molecular 
 LEGO® to cope with the pressure from combinatorial science to synthesize\
 , screen and identify one out of thousands – millions of compounds. Durin
 g investigations of combined Peptide diversity\, we more or less serendip
 itously discovered the CuAAC click reaction in 2001. The mechanism of the
  reaction will be discussed and its application in a variety of studies i
 nvolving immobilization\, mimicry\, structural control and protein ligati
 on will be presented. The more existential aspects of our fundamental und
 erstanding of chemistry\, the importance of serendipity\, and our pledge 
 to the young to study chemistry for a better future\, will also be discus
 sed.[nl][nl]\n\nRegister here: https://www.conferencemanager.dk/meldal [n
 l][nl]\n\nMorten Meldal\, Professor in chemistry at the University of Cop
 enhagen\, received the Nobel Prize in Chemistry in 2022. He was awarded j
 ointly with Carolyn R. Bertozzi and K. Barry Sharpless "for the developme
 nt of click chemistry and bioorthogonal chemistry". [nl][nl]\n\nChemists 
 strive to build increasingly complicated molecules. For a long time\, thi
 s has been very time consuming and expensive. Click chemistry means that 
 molecular building blocks snap together quickly and efficiently. In 2002\
 , Morten Meldal and Barry Sharpless\, independently of each other\, devel
 oped an elegant and efficient chemical reaction: the copper catalysed azi
 de-alkyne cycloaddition. This is now in widespread use and is utilised in
  the development of pharmaceuticals\, for mapping DNA and creating new ma
 terials.[nl][nl]\n\nPhoto: Lars Krabbe
DTEND:20230329T103000Z
DTSTAMP:20260612T045352Z
DTSTART:20230329T091500Z
LOCATION:DIAS\, Fioniavej 34\, 5230\, Odense M
SEQUENCE:0
SUMMARY:DIAS Nobel Colloquium: Morten Meldal\, Danish Nobel Prize-Winner
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